STAT2 Antibody
Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN- is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P52630
Host
Mouse
Reactivity
Human
Immunogen
A recombinant full-length human protein was used as the immunogen for this STAT2 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
STAT2/2650
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the STAT2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This STAT2 antibody is available for research use only.
Storage Conditions
Store the STAT2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the STAT2 antibody should be determined by the researcher.
Location
Cell surface
Image Legend
Frequently Asked Questions
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