P73 Antibody
The p53 gene is a widely studied anti-oncogene, or tumor suppressor gene. The p53 gene product can act as a negative regulator of cell growth in response to DNA damage. Mutations and allelic loss of the p53 gene have been associated with malignant transformation in a wide variety of human tumors. p53 shares considerable sequence similarity with p73, a gene that maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, p73 does not appear to be activated by DNA damaging agents.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
O15350
Host
Mouse
Reactivity
Human
Immunogen
A recombinant full-length human protein was used as the immunogen for this p73 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
P73/2531
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the p73 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This p73 antibody is available for research use only.
Storage Conditions
Store the p73 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the p73 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
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