PD-L1 Antibody / B7-H1 / CD274
PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
Product Specifications
UniProt
Q9NZQ7
Host
Mouse
Immunogen
A portion of amino acids 39-191 from the human protein was used as the immunogen for this PD-L1 antibody.
Clonality
Monoclonal
Isotype
IgG1 κ
Applications
ELISA
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the PD-L1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This PD-L1 antibody is available for research use only.
CAS Number
9007-83-4
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