PAX5 Antibody
The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 2-4 µg/mL, Immunohistochemistry (FFPE) : 2-4 µg/mL for 30 minutes at RT
UniProt
Q02548
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 235-382 from the human protein was used as the immunogen for the PAX5 antibody.
Clonality
Monoclonal
Isotype
IgG1 λ
Clone
PAX5/3735
Applications
WB, IHC-P
Purity
Protein G affinity chromatography
Format
Biotin Conjugate
Buffer
0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the PAX5 antibody at 2-8oC (up to one month) or aliquot and store at -20oC (longer term).
Limitations
This PAX5 antibody is available for research use only.
Storage Conditions
Store the PAX5 antibody at 2-8°C (up to one month) or aliquot and store at -20°C (longer term) .
Product Datasheet
https://www.nsjbio.com/tds-pdf/pax5-antibody-pax53735-v7997btn
Formulation
0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the PAX5 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
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