PAX5 Antibody
The PAX5 gene is a member of thepaired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conservedDNA-binding domain, known as thepaired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute toneoplastic transformation. The PAX5 gene encodes theB-celllineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development andspermatogenesis.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (order BSA-free format for coating), Western blot: 1-2 µg/mL
UniProt
Q02548
Host
Mouse
Reactivity
Human
Immunogen
Full length human recombinant protein was used as the immunogen for this PAX5 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
PAX5/2060
Applications
ELISA, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the PAX5 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This PAX5 antibody is available for research use only.
Storage Conditions
Store the PAX5 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the PAX5 antibody should be determined by the researcher.
Location
Nuclear
Documents
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