Recombinant ODC1 Antibody / Ornithine Decarboxylase
Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1) . ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 0.25-0.5 µg/mL, Western blot: 0.5-1 µg/mL
UniProt
P11926
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human ODC-1 protein was used as the immunogen for this recombinant ODC1 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RODC1/485
Type
Recombinant
Applications
IHC-P, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the recombinant ODC1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant ODC1 antibody is available for research use only.
Storage Conditions
Store the recombinant ODC1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant ODC1 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Western blot testing of human PC-3 cell lysate with recombinant ODC1 antibody. Predicted molecular weight ~51 kDa.
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