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DSG3 Antibody / Desmoglein 3

Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P32926

Host

Mouse

Reactivity

Human

Immunogen

Amino acids 379-491 were used as the immunogen for the DSG3 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

CFM6-1

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the DSG3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This DSG3 antibody is available for research use only.

Storage Conditions

Store the DSG3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the DSG3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cell surface

Image Legend

IHC staining of FFPE human esophageal carcinoma with DSG3 antibody (clone CFM6-1) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
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