Recombinant NGF Receptor Antibody / p75NTR / CD271
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR) . NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL (not suitable for frozen sample testing), Western blot: 1-2 µg/mL
UniProt
P08138
Host
Mouse
Reactivity
Human
Immunogen
A recombinant human partial protein (amino acids 281-421) was used as the immunogen for this recombinant NGF Receptor antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RNGFR/1965
Type
Recombinant
Applications
IHC-P, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the recombinant NGF Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant NGF Receptor antibody is available for research use only.
Storage Conditions
Store the recombinant NGF Receptor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant NGF Receptor antibody should be determined by the researcher.
Location
Cell surface, cytoplasmic
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Uncoated Human NRP2 (Neuropilin 2) ELISA Kit
Uncoated Human NRP2 (Neuropilin 2) ELISA Kit
Vimentin (VM1170), CF488A conjugate, 0.1mg/mL
