Recombinant MUC2 Antibody / Mucin 2
Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2) . This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
Q02817
Host
Mouse
Reactivity
Human
Immunogen
Amino acids KYPTTTPISTTTMVTPTPTPTGTQTPTTT were used as the immunogen for this recombinant MUC2 antibody. Its epitope has been defined as GTQTP.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RMLP/842
Type
Recombinant
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the recombinant MUC2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant MUC2 antibody is available for research use only.
Storage Conditions
Store the recombinant MUC2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Product Datasheet
https://www.nsjbio.com/tds-pdf/recombinant-muc2-antibody-mucin-2-rmlp842-v7968
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant MUC2 antibody should be determined by the researcher.
Location
Cell surface, cytoplasmic
Image Legend
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