Cytokeratin 3 Antibody / KRT3

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins, which are arranged in pairs of heterotypic keratin chains co-expressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P12035

Host

Mouse

Reactivity

Human

Immunogen

A recombinant full-length human protein was used as the immunogen for this Cytokeratin 3 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

KRT3/2130

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the Cytokeratin 3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This Cytokeratin 3 antibody is available for research use only.

Storage Conditions

Store the Cytokeratin 3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the Cytokeratin 3 antibody should be determined by the researcher.

Location

Cytoplasmic

Image Legend

IHC staining of FFPE human skin with Cytokeratin 3 antibody (clone KRT3/2130) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.