Recombinant TIMP2 Antibody
It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2) . It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A) . It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B) . TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P16035
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids DSGNDIYGNPI (N-terminal region) were used as the immunogen for the recombinant TIMP2 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RTIMP2/2335
Type
Recombinant
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the recombinant TIMP2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant TIMP2 antibody is available for research use only.
Storage Conditions
Store the recombinant TIMP2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant TIMP2 antibody should be determined by the researcher.
Location
Cytoplasmic, cell surface, secreted
Image Legend
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