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ITGAV Antibody

Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Product Specifications

CAS Number

9007-83-4

Specifications

ELISA (order BSA-free format for coating), Flow cytometry: 1-2ug/10^6 cells in 0.1ml, Immunofluorescence: 1-2 µg/mL, Western blot: 1-2 µg/mL

UniProt

P06756

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human full-length integrin alpha V beta 1 protein was used as the immunogen for the ITGAV antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

ITGAV/1610

Applications

ELISA, FACS, IF, WB

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the ITGAV antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This ITGAV antibody is available for research use only.

Storage Conditions

Store the ITGAV antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

Optimal dilution of the ITGAV antibody should be determined by the researcher.

Location

Cell surface, cytoplasmic

Image Legend

SDS-PAGE analysis of purified, BSA-free ITGAV antibody (clone ITGAV/1610) as confirmation of integrity and purity.

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