CDH17 Antibody / Cadherin 17

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin (Cadherin 17, CDH17) may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

Q12864

Host

Mouse

Reactivity

Human

Immunogen

Amino acids 242-418 were used as the immunogen for the CDH17 antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

CDN17-1

Applications

WB, IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the CDH17 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This CDH17 antibody is available for research use only.

Storage Conditions

Store the CDH17 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the CDH17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cell surface, cytoplasmic

Image Legend

Western blot testing of human small intestine lysate with CDH17 antibody (clone CDN17-1) . Predicted molecular weight ~92 kDa but may be observed at higher molecular weights due to glycosylation.