Recombinant Tenascin C Antibody

Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 2-4 µg/mL

UniProt

P24821

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full length human TNC protein was used as the immunogen for the Tenascin C antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG1 k

Clone

RTNC/3635

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the Tenascin C antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This Tenascin C antibody is available for research use only.

Storage Conditions

Store the Tenascin C antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the Tenascin C antibody should be determined by the researcher.

Location

Connective tissue matrix

Image Legend

IHC staining of FFPE human lung carcinoma with Tenascin C antibody (clone rTNC/3635) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.