PD-L1 Antibody / B7-H1 / CD274
PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (order BSA-free format for coating)
UniProt
Q9NZQ7
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 39-191 from the human protein was used as the immunogen for this PD-L1 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
PDL1/2742
Applications
ELISA
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the PD-L1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This PD-L1 antibody is available for research use only.
Storage Conditions
Store the PD-L1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the PD-L1 antibody should be determined by the researcher.
Location
Cell surface, cytoplasmic
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
GPR10 (PRLHR) (2nd Extracel. Dom.) Rabbit Polyclonal Antibody
