CLEC9A Antibody / DNGR-1
This MAb recognizes a protein of 27kDa, identified as CLEC9A (C-type lectin domain family 9 member A) . Its epitopes maps in aa 50-110. The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-9A, also known as DNGR1 (dendritic cell natural killer lectin group receptor 1), is a 241 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Expressed in myeloid lineage cells, brain, spleen and thymus, CLEC-9A is a group V C-type lectin- like receptor (CTLR) that acts as an activation receptor.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/10^6 cells in 0.1ml, Immunofluorescence: 1-2 µg/mL
UniProt
Q8RU4
Host
Mouse
Reactivity
Human
Immunogen
RBL-2H3 cells expressing human CLEC9A fused to an HA epitope. Its epitope maps to within amino acids 50-110.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
8F9
Applications
FACS, IF
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the CLEC9A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CLEC9A antibody is available for research use only.
Storage Conditions
Store the CLEC9A antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the CLEC9A antibody should be determined by the researcher.
Image Legend
SDS-PAGE analysis of purified, BSA-free CLEC9A antibody (clone 8F9) as confirmation of integrity and purity.
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