Glyoxalase 1 Antibody / GLO1

GLO1 is an enzyme involved in the detoxification of methylgyoxal, a byproduct of glycolysis. GLO1 expression has been demonstrated by several studies to be upregulated in various human malignant tumors, including metastatic melanoma and lung carcinoma, and thus is a target for pharmaceutical development.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

Q04760

Host

Mouse

Reactivity

Human

Immunogen

Full length human recombinant protein was used as the immunogen for the Glyoxalase 1 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

CPTC-GLO1-3

Applications

WB, IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the Glyoxalase 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This Glyoxalase 1 antibody is available for research use only.

Storage Conditions

Store the Glyoxalase 1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

Optimal dilution of the Glyoxalase 1 antibody should be determined by the researcher.

Location

Cytoplasmic

Image Legend

IHC testing of FFPE human thyroid carcinoma stained with Glyoxalase 1 antibody (clone CPTC-GLO1-3) . Required HIER: boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.