Growth Hormone Antibody / GH1
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly) .
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P01241
Host
Mouse
Reactivity
Human
Immunogen
A full-length of human Growth Hormone protein was used as the immunogen for the Growth Hormone antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
GH/3155
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the Growth Hormone antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Growth Hormone antibody is available for research use only.
Storage Conditions
Store the Growth Hormone antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the Growth Hormone antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
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