CD15 Antibody / SSEA-1
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on 95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/million cells in 0.1ml, Immunofluorescence: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P22083
Host
Mouse
Reactivity
Human
Immunogen
Human U937 cells were used as the immunogen for the CD15 antibody.
Clonality
Monoclonal
Isotype
IgM k
Clone
SPM119
Applications
FACS, IF, IHC-P
Purity
PEG precipitation
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the CD15 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD15 antibody is available for research use only.
Storage Conditions
Store the CD15 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the CD15 antibody should be determined by the researcher.
Image Legend
Flow cytometry testing of human monocytes with CD15 antibody (clone SPM119) ; Green=isotype control, Red= CD15 antibody.
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