Recombinant Frataxin Antibody / FXN
Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.
Product Specifications
CAS Number
9000-83-3
Specifications
ELISA (order BSA-free format for coating)
UniProt
Q16595
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 57-210 from the human protein were used as the immunogen for this FXN antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RFXN/2124
Type
Recombinant
Applications
ELISA
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the recombinant Frataxin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant Frataxin antibody is available for research use only.
Storage Conditions
Store the recombinant Frataxin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant Frataxin antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
SDS-PAGE analysis of purified, BSA-free recombinant FXN antibody (clone rFXN/2124) as confirmation of integrity and purity.
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