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FOLH1 Antibody / Folate Hydrolase 1

Folate hydrolase 1 (FOLH1), also known as Prostate-specific membrane antigen (PSMA), is a type II transmembrane glycoprotein belonging to the M28 peptidase family. FOLH1 has two enzymatic activities, one as a prostate-specific integral membrane folate hydrolase and the other as a carboxypeptidase In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

Q04609

Host

Mouse

Reactivity

Human, Cat, Dog, Horse

Immunogen

A portion of amino acids 232-433 from the human protein were used as the immunogen for this FOLH1 antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

FOLH1/2354

Applications

WB, IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the FOLH1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This FOLH1 antibody is available for research use only.

Storage Conditions

Store the FOLH1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the FOLH1 antibody should be determined by the researcher.

Location

Cytoplasmic, cell surface

Image Legend

Western blot testing of human LNCaP cell lysate with FOLH1 antibody (clone FOLH1/2354) . Predicted molecular weight ~100 kDa.

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