FABP5 Antibody
This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential.
Product Specifications
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 1-2 µg/mL
UniProt
Q01469
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full length human protein was used as the immunogen for the FABP5 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
FABP5/3750
Applications
IHC-P, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the FABP5 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This FABP5 antibody is available for research use only.
Storage Conditions
Store the FABP5 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Product Datasheet
https://www.nsjbio.com/tds-pdf/fabp5-antibody-fabp53750-v7766
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the FABP5 antibody should be determined by the researcher.
CAS Number
9007-83-4
Location
Nuclear, cytoplasmic
Image Legend
Western blot testing of human HeLa cell lysate with FABP5 antibody. Predicted molecular weight ~15 kDa.
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