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Recombinant FOLH1 Antibody / Folate Hydrolase 1

Folate hydrolase 1 (FOLH1), also known as Prostate-specific membrane antigen (PSMA), is a type II transmembrane glycoprotein belonging to the M28 peptidase family. FOLH1 has two enzymatic activities, one as a prostate-specific integral membrane folate hydrolase and the other as a carboxypeptidase In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer.

Product Specifications

CAS Number

9000-83-3

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

Q04609

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 232-433 from the human protein were used as the immunogen for this recombinant FOLH1 antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG

Clone

FOLH1/3149R

Type

Recombinant

Applications

IHC-P

Purity

Protein A affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the recombinant FOLH1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This recombinant FOLH1 antibody is available for research use only.

Storage Conditions

Store the recombinant FOLH1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the recombinant FOLH1 antibody should be determined by the researcher.

Location

Cytoplasmic, cell surface

Image Legend

IHC testing of FFPE human prostate cancer with recombinant FOLH1 antibody (clone FOLH1/3149R) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.

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