ZNF690 Antibody / ZSCAN29

Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 690 (ZNF690), also known as ZSCAN29, is a 851 amino acid member of the Kruppel C2H2- type zinc finger protein family. Localized to the nucleus, ZNF690 contains six C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional regulation. Four isoforms of ZNF690 exist as a result of alternative splicing events.

Product Specifications

CAS Number

9007-83-4

Specifications

ELISA (order BSA-free format for coating), Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

Q8IWY8

Host

Mouse

Reactivity

Human

Immunogen

A recombinant full-length human ZSCAN29/ZNF690 protein was used as the immunogen for the ZNF690 antibody

Clonality

Monoclonal

Isotype

IgG1 k

Clone

ZSCAN29/2610

Applications

ELISA, IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the ZNF690 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This ZNF690 antibody is available for research use only.

Storage Conditions

Store the ZNF690 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

Optimal dilution of the ZNF690 antibody should be determined by the researcher.

Location

Cytoplasmic, nuclear

Image Legend

IHC staining of FFPE human breast carcinoma with ZNF690 antibody (clone ZSCAN29/2610) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.