Beta Tubulin Antibody / TUBB3
This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 1-2 µg/mL
UniProt
Q13509
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 437-450 were used as the immunogen for the Beta Tubulin antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
TUBB3/3732
Applications
IHC-P, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the Beta Tubulin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Beta Tubulin antibody is available for research use only.
Storage Conditions
Store the Beta Tubulin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the Beta Tubulin antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Western blot testing of human U-87 cel lysate with Beta Tubulin antibody (clone TUBB3/3732) . Predicted molecular weight: ~50 kDa.
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