Drebrin 1 Antibody

Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections. Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS. Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (By similarity) . Involved in memory-related synaptic plasticity in the hippocampus (By similarity) . [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

Q16643

Host

Mouse

Reactivity

Human

Immunogen

Amino acids 150-281 were used as the immunogen for the Drebrin 1 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

DRBP1-1

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the Drebrin 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This Drebrin 1 antibody is available for research use only.

Storage Conditions

Store the Drebrin 1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Drebrin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic

Image Legend

IHC staining of FFPE human brain with Drebrin 1 antibody (clone DRBP1-1) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.