FOLH1 Antibody / PSMA

Folate hydrolase 1 (FOLH1), also known as Prostate-specific membrane antigen (PSMA), has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

Q04609

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 232-433 from the human protein was used as the immunogen for this FOLH1 antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

GCP2-1

Applications

WB, IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the FOLH1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This FOLH1 antibody is available for research use only.

Storage Conditions

Store the FOLH1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

The stated application concentrations are suggested starting points. Titration of the FOLH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.