Granzyme B Antibody
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. [UniProt]
Product Specifications
UniProt
P10144
Host
Mouse
Immunogen
Amino acids 73-187 were used as the immunogen for the Granzyme B antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Applications
WB, IHC-P
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the Granzyme B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Granzyme B antibody is available for research use only.
CAS Number
9007-83-4
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