NRG1 Antibody / Neuregulin-1
Neuregulin-1, also called Heregulin-1, is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD) .
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
Q02297
Host
Mouse
Reactivity
Human
Immunogen
A recombinant human partial protein (amino acids 21-242) was used as the immunogen for the NRG1 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
HRGA1-1
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the NRG1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This NRG1 antibody is available for research use only.
Storage Conditions
Store the NRG1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the NRG1 antibody should be determined by the researcher.
Location
Cell surface, cytoplasmic
Image Legend
Documents
Frequently Asked Questions
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