Recombinant CD79b Antibody

CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.

Product Specifications

CAS Number

9000-83-3

Specifications

ELISA (order BSA-free format for coating) : 2-4 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P40259

Host

Rabbit

Reactivity

Human

Immunogen

A recombinant human partial protein (amino acids 29-159) was used as the immunogen for this recombinant CD79b antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG κ

Clone

IGB/3170R

Type

Recombinant

Applications

ELISA, IHC-P

Purity

Protein A affinity chromatography

Format

Purified

Buffer

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the recombinant CD79b antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This recombinant CD79b antibody is available for research use only.

Storage Conditions

Store the recombinant CD79b antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

Optimal dilution of the recombinant CD79b antibody should be determined by the researcher.

Location

Cell surface

Image Legend

IHC staining of FFPE human tonsil tissue with recombinant CD79b antibody (clone IGB/3170R) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.