PHB Antibody / Prohibitin

This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Ant-iproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. [RefSeq]

Product Specifications

CAS Number

9007-83-4

Specifications

Immunofluorescence: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)

UniProt

P35232

Host

Mouse

Reactivity

Human

Immunogen

A recombinant human partial protein corresponding to amino acids 167-261 was used as the immunogen for the PHB antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

PBTN-1

Applications

IHC-P, IF

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the PHB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This PHB antibody is available for research use only.

Storage Conditions

Store the PHB antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Location

Cytoplasmic

Image Legend

IHC testing of FFPE human liver tissue with PHB antibody (clone PBTN-1) . Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.