CD43 Antibody
CD43 is one of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity) . During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity) . [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
P16150
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human SPN protein was used as the immunogen for the CD43 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
CDLA43-2
Applications
FACS, IF, IHC-P, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the CD43 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD43 antibody is available for research use only.
Storage Conditions
Store the CD43 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the CD43 antibody should be determined by the researcher.
Location
Cell surface
Image Legend
Immunofluorescence staining of human K562 cells with CD43 antibody (green, clone CDLA43-2) and NucSpot Live 650 (red) .
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