PD-L2 Antibody

PD-L2/PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL, Flow cytometry: 1-2ug/10^6 cells, Immunofluorescence: 1-2 µg/mL

UniProt

Q9BQ51

Host

Mouse

Reactivity

Human

Immunogen

A recombinant fragment of human PD-L2 protein within amino acids 27-220 was used as the immunogen for the PD-L2 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

CDLA273-1

Applications

WB, IF, FACS

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the PD-L2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This PD-L2 antibody is available for research use only.

Storage Conditions

Store the PD-L2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

Optimal dilution of the PD-L2 antibody should be determined by the researcher.

Location

Cytoplasm, cell surface

Image Legend

Western blot testing of 1) human Raji and 2) mouse RAW264.7 cell lysate with PD-L2 antibody (clone CDLA273-1) . Expected molecular weight: 31-60 kDa depending on glycosylation level.