Camellianin A

Camellianin A, the main flavonoid in A. nitida leaves, displays anticancer activity and angiotensin converting enzyme (ACE) -inhibitory activity. Camellianin A inhibits the proliferation of the human Hep G2 and MCF-7 cell lines and induces the significant increase of the G0/G1 cell population[1][2].

Product Specifications

CAS Number

[109232-77-1]

UNSPSC

12352005

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/camellianin-a.html

Purity

99.17

Solubility

10 mM in DMSO

Smiles

O[C@H]([C@@H](O)[C@@H]1O[C@@](O[C@@H](C)[C@H](O)[C@H]2O)([H])[C@@H]2O)[C@@H](O[C@@H]1COC(C)=O)OC3=C(C4=O)C(OC(C5=CC=C(O)C=C5)=C4)=CC(O)=C3

Molecular Formula

C29H32O15

Molecular Weight

620.56

References & Citations

[1]Gao H, et al. Anti-proliferative effect of camellianin A in Adinandra nitida leaves and its apoptotic induction in human Hep G2 and MCF-7 cells. Molecules. 2010 May 28;15 (6) :3878-86.|[2]Liu B, et al. Antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of ethanol extract and pure flavonoids from Adinandra nitida leaves. Pharm Biol. 2010 Dec;48 (12) :1432-8.