ICOS Ligand Antibody / ICOS-L / B7RP-1
Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity) . [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
O75144
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment of human ICOSLG / B7RP-1 protein within amino acids 23-149 was used as the immunogen for the ICOS Ligand antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
ISLG-1
Applications
IHC-P, IF, FACS
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the ICOS Ligand antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This ICOS Ligand antibody is available for research use only.
Storage Conditions
Store the ICOS Ligand antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cell surface
Image Legend
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