Recombinant ICAM3 Antibody
Recognizes an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C.
Product Specifications
CAS Number
9000-83-3
Specifications
Blocks binding of CD11a (LFA-1) to CD50 (ICAM-3) (order BSA/sodium azide-free format), Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
P32942
Host
Rabbit
Reactivity
Human
Immunogen
Full length recombinant human protein was used as the immunogen for the recombinant ICAM3 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
ICAM3/2873R
Type
Recombinant
Applications
Blocking, IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the recombinant ICAM3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant ICAM3 antibody is available for research use only.
Storage Conditions
Store the recombinant ICAM3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Membrane, cytoplasm
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