SOX9 Antibody
Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Western blot: 1-2 µg/mL
UniProt
P48436
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 393-508 from the human protein was used as the immunogen for the SOX9 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
SOX9/2398
Applications
IHC-P, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the SOX9 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This SOX9 antibody is available for research use only.
Storage Conditions
Store the SOX9 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Nuclear
Image Legend
Western blot testing of human HepG2 cell lysate with SOX9 antibody. Predicted molecular weight: 56-65 kDa.
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