Carboxypeptidase A1 Antibody / CPA1

The CPA1 gene encodes Carboxypeptidase A1, a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [RefSeq]

Product Specifications

CAS Number

9007-83-4

Specifications

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

UniProt

P15085

Host

Mouse

Reactivity

Human

Immunogen

Full length recombinant human protein was used as the immunogen for the Carboxypeptidase A1 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

CBPA1-1

Applications

IHC-P

Purity

Protein G affinity

Format

Purified

Buffer

Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Reconstitution

Store the Carboxypeptidase A1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This Carboxypeptidase A1 antibody is available for research use only.

Storage Conditions

Store the Carboxypeptidase A1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*

Location

Cytoplasmic, secreted

Image Legend

IHC testing of FFPE human pancreas with Carboxypeptidase A1 antibody (clone CBPA1-1) . HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.