Cystatin D (Human, Highly Pure)

<strong>Cystatin D (Human, Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2010472_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 15.2 kDa_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure human Cystatin D (produced in HEK293 cells). Cystatin D is a natual inhibitor of papain-like peptidases._x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> CST5, MGC71922_x000D_ <strong>Grade:</strong> Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Shu Y, Chang Y, Wu H, Li J, Cao B, Sun X, Wang J, Peng L, Hu X, Yu X, Qiu W._x000D_ Serum cystatin C and anti-N-methyl-D-aspartate receptor encephalitis. Acta_x000D_ Neurol Scand. 2018 May;137(5):515-522._x000D_ _x000D_ 2: Peng Q, Zhao J, Wang P, Huang C, Chen B, Song J, Xu G. Expressions of plasma_x000D_ cystatin C, D-dimer and hypersensitive C-reactive protein in patients with_x000D_ intracranial progressive hemorrhagic injury after craniocerebral injury, and_x000D_ their clinical significance. Arq Neuropsiquiatr. 2019 Jul 15;77(6):381-386._x000D_ _x000D_ 3: Ferrer-Mayorga G, Alvarez-Díaz S, Valle N, De Las Rivas J, Mendes M, Barderas_x000D_ R, Canals F, Tapia O, Casal JI, Lafarga M, Muñoz A. Cystatin D locates in the_x000D_ nucleus at sites of active transcription and modulates gene and protein_x000D_ expression. J Biol Chem. 2015 Oct 30;290(44):26533-48._x000D_ _x000D_ 4: Laurent-Matha V, Huesgen PF, Masson O, Derocq D, Prébois C, Gary-Bobo M,_x000D_ Lecaille F, Rebière B, Meurice G, Oréar C, Hollingsworth RE, Abrahamson M,_x000D_ Lalmanach G, Overall CM, Liaudet-Coopman E. Proteolysis of cystatin C by_x000D_ cathepsin D in the breast cancer microenvironment. FASEB J. 2012_x000D_ Dec;26(12):5172-81._x000D_ _x000D_ 5: Alvarez-Díaz S, Valle N, García JM, Peña C, Freije JM, Quesada V, Astudillo_x000D_ A, Bonilla F, López-Otín C, Muñoz A. Cystatin D is a candidate tumor suppressor_x000D_ gene induced by vitamin D in human colon cancer cells. J Clin Invest. 2009_x000D_ Aug;119(8):2343-58._x000D_ _x000D_ 6: Hill LJ, Di Pietro V, Hazeldine J, Davies D, Toman E, Logan A, Belli A._x000D_ Cystatin_D (CST5): An ultra-early inflammatory biomarker of traumatic brain_x000D_ injury. Sci Rep. 2017 Jul 10;7(1):5002._x000D_ _x000D_ 7: Deng Y, Ma J, Hou Y, Zhou D, Hou T, Li J, Liang S, Tan N, Chen C. Combining_x000D_ Serum Cystatin C and Urinary N-Acetyl-Beta-D-Glucosaminidase Improves the_x000D_ Precision for Acute Kidney Injury Diagnosis after Resection of Intracranial_x000D_ Space-Occupying Lesions. Kidney Blood Press Res. 2020;45(1):142-156._x000D_ _x000D_ 8: Nashida T, Sato R, Haga-Tsujimura M, Yoshie S, Yoshimura K, Imai A, Shimomura_x000D_ H. Antigen-presenting cells in parotid glands contain cystatin D originating_x000D_ from acinar cells. Arch Biochem Biophys. 2013 Feb 1;530(1):32-9._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/26253993/">9: Ho J, Tangri N, Komenda P, Kaushal A, Sood M, Brar R, Gill K, Walker S,_x000D_ MacDonald K, Hiebert BM, Arora RC, Rigatto C. Urinary, Plasma, and Serum_x000D_ Biomarkers' Utility for Predicting Acute Kidney Injury Associated With Cardiac_x000D_ Surgery in Adults: A Meta-analysis. Am J Kidney Dis. 2015 Dec;66(6):993-1005.</a>_x000D_ _x000D_ <strong>Products Related to Cystatin D (Human, Highly Pure)</strong><a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>