FTL Antibody / Ferritin Light Chain
Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III) . Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 0.1-0.2 µg/mL for 30 min at RT
UniProt
P02792
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 38-165 from the human protein were used as the immunogen for this FTL antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
FTL/1387
Applications
WB, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the FTL antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This FTL antibody is available for research use only.
Storage Conditions
Store the FTL antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Location
Cytoplasmic
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
LDOC1L, CT (LDOC1L, MAR6, MART6, Protein LDOC1L, Leucine zipper protein down-regulated in cancer cells-like, Mammalian retrotransposon-derived protein 6) (APC)
LDOC1L, CT (LDOC1L, MAR6, MART6, Protein LDOC1L, Leucine zipper protein down-regulated in cancer cells-like, Mammalian retrotransposon-derived protein 6) (APC)