FTL Antibody / Ferritin Light Chain
Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III) . Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
Product Specifications
Specifications
UniProt
P02792
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 38-165 from the human protein were used as the immunogen for this FTL antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
FTL/1387
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the FTL antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This FTL antibody is available for research use only.
Storage Conditions
Store the FTL antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Product Datasheet
https://www.nsjbio.com/tds-pdf/ftl-antibody-ferritin-light-chain-ftl1387-v7412
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
CAS Number
9007-83-4
Location
Cytoplasmic
Image Legend
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