BMI1 Antibody
The B cell-specific moloney murine leukemia virus integration site 1 (Bmi-1) is a transcriptional receptor of the polycomb gene family involved in several cellular processes including cell-cycle regulation, apoptosis, and maintenance of adult and neoplastic stem cells by providing self-renewal capacity. Further, Bmi-1 expression has been associated with malignant transformation, tumor progression, metastatic disease, and poor prognosis in human malignancies.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL, Prediluted IHC only format: incubate for 30 min at RT (1)
UniProt
P35226
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 142-326 from the human protein was used as the immunogen for the BMI1 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
PGRF4-1
Applications
IHC-P, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the BMI1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This BMI1 antibody is available for research use only.
Storage Conditions
Store the BMI1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Nuclear
Image Legend
Western blot testing of human 293T lysate with BMI1 antibody (clone PGRF4-1) . Expected molecular weight: 37-43 kDa.
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