Recombinant Keratin 18 Antibody / Cytokeratin 18
Keratin 18 (KRT18) is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood. [Wiki]
Product Specifications
CAS Number
9000-83-3
Specifications
UniProt
P05783
Host
Rabbit
Reactivity
Human
Immunogen
Human full length recombinant protein was used as the immunogen for the recombinant Keratin 18 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
CTKN18-2R
Type
Recombinant
Applications
WB, IHC-P, FACS
Purity
Protein A affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the recombinant Keratin 18 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant Keratin 18 antibody is available for research use only.
Storage Conditions
Store the recombinant Keratin 18 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic
Image Legend
Western blot testing of human HCT116 antibody with recombinant Keratin 18 antibody (clone CTKN18-2R) . Predicted molecular weight ~48 kDa.
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