Calretinin Antibody / CALB2 / Calbindin 2
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. Calretinin/Calbindin 2 plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [RefSeq]
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)
UniProt
P22676
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 23-242 from the human protein was used as the immunogen for the Calretinin antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
CLRT-1
Applications
IHC-P
Purity
Protein G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the Calretinin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Calretinin antibody is available for research use only.
Storage Conditions
Store the Calretinin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Nuclear, cytoplasmic
Image Legend
Frequently Asked Questions
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