RPA32 Antibody / Replication Protein A2
Recognizes a protein of 34kDa, identified as a subunit of Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB). RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). It is involved in DNA replication, repair, and recombination. RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase (pol) alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.
Product Specifications
CAS Number
9007-83-4
UniProt
P15927
Host
Mouse
Immunogen
Full length recombinant human protein was used as the immunogen for this RPA32 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Applications
IHC-P
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the RPA32 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This RPA32 antibody is available for research use only.
Frequently Asked Questions
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