RPA32 Antibody / Replication Protein A2
Recognizes a protein of 34kDa, identified as a subunit of Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB). RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). It is involved in DNA replication, repair, and recombination. RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase (pol) alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.
Product Specifications
UniProt
P15927
Host
Mouse
Immunogen
Full length recombinant human protein was used as the immunogen for this RPA32 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Applications
WB
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the RPA32 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This RPA32 antibody is available for research use only.
CAS Number
9007-83-4
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