CK20 Antibody / Cytokeratin 20 / KRT20
This mAb recognizes an intermediate filament protein of 46kDa, identified as Cytokeratin 20 (KRT20, CK20) . KRT is abundantly expressed in goblet cells and enterocytes of the gastrointestinal tract. It is a useful marker of pancreatic and colorectal cancer. KRT20 is expressed under normal, hyperplastic and neoplastic conditions. It has been detected in adenocarcinomas of the colon, stomach and biliary tract. Breast carcinomas are generally non-reactive.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P35900
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 196-323 from the human protein was used as the immunogen for this CK20 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
KRT20/1993
Applications
WB, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the CK20 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CK20 antibody is available for research use only.
Storage Conditions
Store the CK20 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic
Image Legend
Western blot testing of human HT29 cell lysate with CK20 antibody (clone KRT20/1993) . Predicted molecular weight ~46 kDa.
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