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MAGEA4 Antibody

The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types, but not in normal tissues, with the exception of testis and placenta.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT

UniProt

P43358

Host

Mouse

Reactivity

Human

Immunogen

Full length human protein was used as the immunogen for the MAGEA4 antibody.

Clonality

Monoclonal

Isotype

IgG2c κ

Clone

CPTC-MAGEA4-1

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the MAGEA4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This MAGEA4 antibody is available for research use only.

Storage Conditions

Store the MAGEA4 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Location

Cytoplasmic, nuclear

Image Legend

IHC testing of FFPE human testis stained with MAGEA4 antibody. Required HIER: boiling tissue sections in 10mM citrate buffer, pH6, for 10-20 min followed by cooling at RT for 20 min.

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