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CD127 Antibody / IL7R

The protein encoded by this gene is a receptor for interleukin 7 (IL7) . The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V (D) J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID) .

Product Specifications

CAS Number

9007-83-4

Specifications

ELISA: order BSA/sodium azide-free format for coating, Western blot: 1-2 µg/mL

UniProt

P16871

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 21-236 from the human protein was used as the immunogen for the CD127 antibody.

Clonality

Monoclonal

Isotype

IgG2c κ

Clone

IL7R/2751

Applications

ELISA, WB

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the CD127 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This CD127 antibody is available for research use only.

Storage Conditions

Store the CD127 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the CD127 antibody should be determined by the researcher.

Location

Cell surface and cytoplasmic

Image Legend

Western blot testing of human cell lysate samples with CD127 antibody (clone IL7R/2751) .

Frequently Asked Questions

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