CD127 Antibody / IL7R
The protein encoded by this gene is a receptor for interleukin 7 (IL7) . The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V (D) J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID) .
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA: order BSA/sodium azide-free format for coating, Western blot: 1-2 µg/mL
UniProt
P16871
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 21-236 from the human protein was used as the immunogen for the CD127 antibody.
Clonality
Monoclonal
Isotype
IgG2c κ
Clone
IL7R/2751
Applications
ELISA, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the CD127 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD127 antibody is available for research use only.
Storage Conditions
Store the CD127 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the CD127 antibody should be determined by the researcher.
Location
Cell surface and cytoplasmic
Image Legend
Western blot testing of human cell lysate samples with CD127 antibody (clone IL7R/2751) .
Frequently Asked Questions
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